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< Sorin Istrail's Homepage :: Research Interests
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"Development of Western science is based on two great achievements:
the invention of the formal logical system (in Euclidean geometry) by the
Greek philosophers, and the discovery of the possibility to find out causal
relationships by systematic experiment (during Renaissance)".
Albert Einstein (1953)
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GENOMIC REGULATORY NETWORKS AND THE REGULATORY GENOME
Research themes:
- sea urchin developmental gene regulatory networks
- building a high-resolution transcriptome map of the embryo
- inferring logic functions of genomic cis-regulatory code and the principles
of information processing of genomic regulation
People: Ryan Tarpine, Rohan Maddamsetti, Sanjay Trehan, and David Moskowitz
Collaborators:
- Eric Davidson (Caltech)
- Russel Turner (Johns Hokins University)
- Gary Wessell (Brown University)
Publications:
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S. Istrail, S. Ben-Tabou De-Leon, E. Davidson, The Regulatory Genome and the Computer. Developmental Biology, vol. 310, issue 2, pp. 187-195 (2007)
- M.P. Samanta, W. Tongprasit, S. Istrail, R.A. Cameron, Q. Tu,
E.H. Davidson, V. Stolc, The Transcriptome of the Sea Urchin Embryo,
Science, vol. 314, pp. 960-962 November (2006)
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E. Sodergren, G. Weinstock, E. Davidson, S. Istrail, The Genome of the Sea Urchin
Strongylocentrotus purpuratus, Science, vol 314., pp. 941-952, November
(2006)
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Sorin Istrail and Eric Davidson, Logic functions of the genomic cis-regulatory code,
Proceedings of the National Academy of Sciences, vol. 102, No. 14, 4954-4959 (2005)
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